High performance liquid chromatography as an aid in picking up hemoglobin H disease
نویسندگان
چکیده
منابع مشابه
Determination of carbamylated hemoglobin by high-performance liquid chromatography.
We have developed an HPLC method for measuring carbamylated hemoglobin (CarHb), based on the quantification of valine hydantoin formed from the released NH2-terminal carbamyl valine residue after acid hydrolysis of hemoglobin. In uremia, CarHb is produced by nonenzymatic post-translational modification of the terminal amino group of hemoglobin monomers by isocyanic acid, derived from the sponta...
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ژورنال
عنوان ژورنال: Indian Journal of Pathology and Microbiology
سال: 2010
ISSN: 0377-4929
DOI: 10.4103/0377-4929.72008